Lizzo Reacts with Shock and Pride to South Park’s Satirical “Lizzo” Drug Episode. In a bold and humorous move, the creators of “South Park” have taken a jab at celebrity weight loss trends by introducing a fictional drug named “Lizzo” in their latest special, “The End of Obesity.” The episode, which premiered this weekend, parodies the increasing use of weight loss drugs such as Ozempic by celebrities and the public. The storyline centers around Eric Cartman, who is desperate to lose weight but finds himself unable to afford Ozempic due to financial constraints and insurance limitations. Instead, Cartman’s doctor prescribes “Lizzo” – a hilariously unconventional remedy.
“She’s a really good singer who talks about body positivity, and just being happy with the way you look,” the doctor explains in the episode. “I want you to listen to Lizzo five times a day and watch her videos just before bedtime. I’m afraid you’ll have to be on Lizzo for the rest of your life.”
In true “South Park” fashion, the episode blends satire and social commentary, with an angry Cartman later lamenting, “Rich people get Ozempic, poor people get body positivity!” The fictional drug “Lizzo” is promoted as a budget-friendly alternative to expensive weight loss medications, costing 90% less than Ozempic. According to a fake advertisement within the episode, “Lizzo” helps users feel good about their weight, with one customer humorously stating, “I lowered my standards and my expectations.”
The ad goes on to claim that 70% of Lizzo users “no longer cared about their weight” and were able to “eat what they want with minimal physical activity,” though it also humorously mentions constipation as a side effect.
Soon after the episode aired, Lizzo, the 36-year-old singer, and advocate for body positivity, posted a video reacting to the portrayal.
“Guys, my worst fear has been actualized. I’ve been referenced in a South Park episode. I’m so scared. I’m going to blind react to it now,” she began. As she watched the scene unfold, her initial shock was evident.
As the fake ad played, her expression shifted from curiosity to a shell-shocked realization. The portrayal of her as a body positivity “drug” took her by surprise. However, Lizzo, known for her candid and unapologetic personality, soon embraced the moment.
“That’s crazy. I just feel like damn, I am really that b****. I really showed the world how to love yourself and not give a f***, to the point where these men in Colorado know who the f*** I am and put it on their cartoon that has been around for 25 years,”
she said.
“I’m really that b**** and I show y’all how to really not give a f*** and I will keep showing you [how to do the same],” Lizzo continued, reaffirming her commitment to promoting self-love and body positivity. Her reaction, filled with a mix of pride and humor, showcased her resilience and the impact she has had on popular culture.
The episode’s satire comes at a time when injectable weight loss drugs like Ozempic, originally intended for managing blood glucose levels in people with type 2 diabetes, are being widely used for weight loss. Many celebrities, including Sharon Osbourne, Rebel Wilson, Amy Schumer, and Oprah Winfrey, have publicly admitted to using semaglutide GLP-1s for their body transformations.
In recent months, the conversation around these drugs has become more intense, with public figures facing scrutiny over their use. Last month, Barbra Streisand faced backlash for asking Melissa McCarthy if she had taken Ozempic, leading Streisand to clarify that she was merely complimenting McCarthy’s appearance.
The “South Park” episode and Lizzo’s subsequent reaction have sparked conversations about body positivity, societal pressures on weight, and the role of satire in addressing these issues. Lizzo’s embrace of the moment, turning potential criticism into a reaffirmation of her message, highlights her influence and the ongoing dialogue about body image and self-acceptance in modern culture.
“South Park” continues to stream on Paramount Plus, delivering its unique blend of irreverent humor and social commentary, now with Lizzo as part of its storied legacy.